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Chicago White Sox vs. Minnesota Twins: Preview, Predictions and Picks for April 22, 2025

Updated on:
Apr 22, 2025 1:16 PM
The Minnesota Twins, looking to bounce back from their current losing streak, host the struggling Chicago White Sox at Target Field on Tuesday, April 22, 2025, at 7:40 PM. The Twins hold a slim 2-1 series lead in their regular season matchup, but the White Sox will look to capitalize on their recent woes. With the Twins holding a 4-5 home record and the White Sox struggling on the road with a 1-9 mark, this AL Central divisional matchup is poised to be a crucial one.
Chicago White Sox vs Minnesota Twins

Current Odds

CHW
MIN
Over
8.0
-125
Under
8.5
+102
CHW
+1.5
+102
MIN
-1.5
-112
CHW
ML
+215
MIN
ML
-240

White Sox vs Twins statistics

Stat White Sox Twins
Hits 139 (30th) 153 (27th)
Batting Average .196 (30th) .211 (27th)
Runs Batted In 68 (27th) 71 (26th)
Runs 70 (27th) 75 (26th)
Home Runs 17 (Tied-24th) 16 (Tied-26th)
Walks 69 (23rd) 59 (Tied-27th)
Stolen Bases 16 (Tied-19th) 12 (24th)
Strikeouts 187 (14th) 183 (Tied-12th)
Pitches 3086 (25th) 3226 (19th)

Minnesota Twins recent games

Game Date Opponent Result Score
4/20/25 @ Atlanta Braves L 6-2
4/19/25 @ Atlanta Braves L 4-3
4/18/25 @ Atlanta Braves L 6-4
4/16/25 vs New York Mets W 4-3 F/10
4/15/25 vs New York Mets W 6-3

Chicago White Sox recent games

Game Date Opponent Result Score
4/21/25 @ Boston Red Sox L 4-2
4/20/25 @ Boston Red Sox W 8-4
4/19/25 @ Boston Red Sox L 4-3 F/10
4/18/25 @ Boston Red Sox L 10-3
4/17/25 vs Athletics L 8-0

Minnesota Twins injuries

  • Willi Castro (2B): Day-To-Day
  • DaShawn Keirsey Jr. (RF): Day-To-Day
  • Pablo Lopez (SP): 15-Day-IL
  • Matt Wallner (RF): 10-Day-IL
  • Michael Tonkin (RP): 15-Day-IL

Chicago White Sox injuries

  • Korey Lee (C): 10-Day-IL
  • Mike Tauchman (RF): 10-Day-IL
  • Fraser Ellard (RP): 15-Day-IL
  • Chase Meidroth (2B): 10-Day-IL
  • Josh Rojas (3B): 10-Day-IL

White Sox vs Twins game info

Type Info
Venue Target Field
Location Minneapolis, Minnesota
First pitch Tue 7:40 PM
Temperature 68°
Chance of Rain 0%

White Sox vs Twins predictions

When looking at the Chicago White Sox lineup, Andrew Benintendi stands out as a player to watch. Currently, with a batting average projection that includes around one hit per game, his ability to get on base could be crucial for the Sox tonight. With teammates like Andrew Vaughn contributing around 0.5 RBI per game, there is potential for Chicago to string together some key offensive plays. Also, Lenyn Sosa's consistency emphasizes his knack for getting on base—opening doors for scoring opportunities despite Chicago's struggles. On the mound, Davis Martin aims to manage the Twins' lineup, projecting an average of five strikeouts over five innings. His performance could be a critical factor in either stifling or allowing the Twins' offense.

On the flip side, the Minnesota Twins have Byron Buxton as their standout performer. Known for his powerful swings, he’s projected to hammer out hits consistently, which often catalyzes rallies for his team. Harrison Bader appears likely to add value with his batting, providing around half an RBI per game. Meanwhile, Bailey Ober, the probable starting pitcher, could set the tone defensively. His potential to keep the White Sox bats at bay by amassing an average of six strikeouts and holding bats to a low number of hits gives Minnesota a formidable edge. Edouard Julien's game could add another layer of intrigue, especially if he continues to find ways to get on base and score runs.

From everything we've pieced together, the Minnesota Twins seem to have the upper hand for this matchup. Sure, both teams have stumbled along this early MLB season, but there’s a sense that the Twins can capitalize on home-field advantage at Target Field. With key players like Buxton likely to impact the game directly on offensive and defensive ends and Ober poised to deliver a strong pitching performance, the momentum leans towards Minnesota securing a much-needed victory. However, don't count the White Sox out just yet. Baseball thrives on surprises, and they might just have a few in store for us. What do you think? Is it a Twins victory in the making, or will the White Sox disrupt the predictions?

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