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Houston Astros vs. St. Louis Cardinals: Preview, Predictions and Picks for April 14, 2025

Updated on:
Apr 15, 2025 7:15 PM
The Houston Astros head to Busch Stadium on Monday, April 14, 2025, to kick off a three-game series against the St. Louis Cardinals. Both teams enter the matchup with identical 7-8 records, with the Astros looking to improve their 3-3 road record and the Cardinals aiming to build on their strong 6-3 home performance. Expect a competitive contest as these two MLB foes clash at 7:45 PM.
Houston Astros vs St. Louis Cardinals

Current Odds

HOU
STL
Over
5.5
-135
Under
7.5
-115
HOU
-1.5
+175
STL
+1.5
-145
HOU
ML
-110
STL
ML
+135

Astros vs Cardinals statistics

Stat Astros Cardinals
Hits 108 (Tied-22nd) 152 (2nd)
Batting Average .219 (22nd) .280 (2nd)
Runs Batted In 53 (Tied-23rd) 78 (4th)
Runs 60 (Tied-21st) 82 (Tied-3rd)
Home Runs 12 (Tied-21st) 18 (Tied-7th)
Walks 60 (Tied-6th) 55 (Tied-15th)
Stolen Bases 16 (10th) 10 (Tied-18th)
Strikeouts 131 (Tied-15th) 125 (Tied-10th)
Pitches 2241 (17th) 2370 (6th)

St. Louis Cardinals recent games

Game Date Opponent Result Score
4/13/25 vs Philadelphia Phillies W 7-0
4/12/25 vs Philadelphia Phillies L 4-1
4/11/25 vs Philadelphia Phillies W 2-0
4/9/25 @ Pittsburgh Pirates L 2-1 F/13
4/8/25 @ Pittsburgh Pirates W 5-3

Houston Astros recent games

Game Date Opponent Result Score
4/13/25 vs Los Angeles Angels W 7-3
4/12/25 vs Los Angeles Angels L 4-1
4/11/25 vs Los Angeles Angels W 14-3
4/9/25 @ Seattle Mariners L 7-6
4/8/25 @ Seattle Mariners W 2-1 F/12

St. Louis Cardinals injuries

  • Nathan Church (LF): Day-To-Day
  • Cooper Hjerpe (SP): Day-To-Day
  • Masyn Winn (SS): 10-Day-IL
  • Drew Rom (SP): Day-To-Day
  • Ivan Herrera (C): 10-Day-IL

Houston Astros injuries

  • Brendan Rodgers (2B): Day-To-Day
  • Kaleb Ort (RP): 15-Day-IL
  • Miguel Ullola (SP): Day-To-Day
  • Glenn Otto (RP): Day-To-Day
  • Ray Gaither (SP): Day-To-Day

Astros vs Cardinals game info

Type Info
Venue Busch Stadium
Location St. Louis, Missouri
First pitch Mon 7:45 PM
Temperature 62°
Chance of Rain 0%

Astros vs Cardinals predictions

In tonight's matchup between the Houston Astros and St. Louis Cardinals, I'm really banking on Jose Altuve and Yordan Alvarez to make an impact. Altuve’s been swinging with a .302 batting average, and I can see him snagging a hit or two and possibly putting a run on the board. Alvarez, on the other hand, has been the go-to guy when it comes to driving in runs, and with his power, I wouldn't be surprised if he belts one out of Busch Stadium. Let's not forget Framber Valdez, who's taking the mound for the Astros. He’s likely to keep it tight, keeping the Cards on their toes while racking up some strikeouts.

Switching sides, the Cardinals have a potent lineup of their own. Brendan Donovan is definitely one to watch; with his impressive .350 average, he's a reliable presence at the plate. I expect him to get on base, and you never know, maybe he'll find his way home to score. Without Ivan Herrera in the mix due to injury, they'll look to others like Nolan Arenado to bring some firepower. With Sonny Gray taking the mound for the Cards, he should keep the Astros’ lineup from running away with the game, though he will need to avoid giving up the big hits.

When it comes down to predicting the winner in this clash, it's all about who executes better on the day. Both teams sit with identical records, making this a pretty evenly matched game. My gut feeling? The Cardinals might just edge it out with their home record, winning six out of the nine games at Busch Stadium so far. The Astros have proven themselves formidable opponents on the road, standing at .500 in such games, so it’ll be close. Expect a game that goes down to the wire, perhaps with the Cardinals narrowly clinching it in the end. What do you think—is it the Cardinals' game to lose?

St. Louis Cardinals

Houston Astros

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