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Cleveland Guardians vs. Los Angeles Angels: Preview, Predictions and Picks for April 6, 2025

Updated on:
Apr 6, 2025 5:19 PM
The Cleveland Guardians, tied 1-1 in the series, travel to Angel Stadium to face the Los Angeles Angels on Sunday, April 6th at 4:07 PM. The Angels, currently 5-3 overall and 1-1 at home, look to take the series lead, while the Guardians aim to even their 3-5 record with a crucial road win. Expect a thrilling matchup in this MLB showdown.
Cleveland Guardians vs Los Angeles Angels

Current Odds

CLE
LAA
Over
7.5
+168
Under
7.5
-125
CLE
+2.5
+313
LAA
-3.5
+320
CLE
ML
+2800
LAA
ML
-5000

Guardians vs Angels statistics

Stat Guardians Angels
Hits 61 (19th) 62 (18th)
Batting Average .234 (15th) .228 (16th)
Runs Batted In 32 (Tied-15th) 40 (Tied-8th)
Runs 32 (Tied-18th) 40 (Tied-9th)
Home Runs 12 (Tied-6th) 10 (Tied-14th)
Walks 28 (Tied-16th) 25 (21st)
Stolen Bases 0 (30th) 4 (Tied-20th)
Strikeouts 67 (12th) 73 (15th)
Pitches 1210 (Tied-17th) 1210 (Tied-17th)

Los Angeles Angels recent games

Game Date Opponent Result Score
4/5/25 vs Cleveland Guardians W 10-4
4/4/25 vs Cleveland Guardians L 8-6
4/2/25 @ St. Louis Cardinals L 12-5
4/1/25 @ St. Louis Cardinals W 9-7 F/11
3/31/25 @ St. Louis Cardinals W 5-4 F/10

Cleveland Guardians recent games

Game Date Opponent Result Score
4/5/25 @ Los Angeles Angels L 10-4
4/4/25 @ Los Angeles Angels W 8-6
4/2/25 @ San Diego Padres L 5-2
4/1/25 @ San Diego Padres L 7-0
3/31/25 @ San Diego Padres L 7-2

Los Angeles Angels injuries

  • Ryan Zeferjahn (RP): Day-To-Day
  • Kelvin Caceres (RP): Day-To-Day
  • Yoan Moncada (3B): Day-To-Day
  • Ryan Johnson (RP): paternity
  • Zach Neto (SS): 10-Day-IL

Cleveland Guardians injuries

  • Jake Anchia (C): Day-To-Day
  • Yordys Valdes (SS): Day-To-Day
  • Slade Cecconi (SP): 15-Day-IL
  • George Valera (RF): Day-To-Day
  • Erik Sabrowski (RP): 15-Day-IL

Guardians vs Angels game info

Type Info
Venue Angel Stadium
Location Anaheim, California
First pitch Sun 4:07 PM
Temperature 53°
Chance of Rain 0%

Guardians vs Angels predictions

As the Cleveland Guardians gear up to face the Los Angeles Angels, all eyes will be on a number of standout players. Steven Kwan, who's been batting at an impressive .367 average, will be crucial at the plate, potentially adding to his solid record with a couple of hits. Meanwhile, Jose Ramirez should be watched closely for his power-hitting potential, as he's already notched four home runs this season. If you're thinking about the RBI game, Kyle Manzardo is the guy to watch with his eight RBIs so far. On the mound, Luis Ortiz's performance could be pivotal. With him projected to last just over five innings, his ability to limit runs and secure strikeouts might turn out to be the Guardians’ key to success. It's a battle where pitching and batting synergy could make or break the game for Cleveland.

Switching gears to the Los Angeles Angels, there's undeniable talent across the board. With Logan O'Hoppe swinging a promising bat at a .320 average and tying in home runs with Ramirez at four, this match could see some fireworks if he finds his rhythm in the box. Mike Trout, a cornerstone in the Angels lineup, could prove to be an RBI machine, given his knack for driving in runs; he's a player you can never count out. Tyler Anderson, the starting pitcher, will need to bring his A-game. Aiming to control the Guardians’ batters while minimizing runs scored, his approach on the mound could largely dictate how the Angels fare defensively.

Assessing both teams' current form and player dynamics, it’s shaping up to be a tightly contested game. The Angels hold a home-field advantage, with records that hint at a slightly better phase compared to the Guardians. Despite an even split in series standings and both having their strengths and weaknesses, the Angels’ slightly stronger hitting stats and ability to hold their own at Angel Stadium leans the prediction in their favor. It wouldn't be surprising to see them edge out a victory, especially if key players like O'Hoppe and Trout hit their stride. Of course, baseball’s charming unpredictability means that anything can happen once that first pitch is thrown, so fans are in for a treat.

Los Angeles Angels

Cleveland Guardians

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